George Clooney And Annette Bening Set For Paul Weitz’s In Love

George Clooney and Annette Bening will lead In Love, a new feature to be directed by Paul Weitz and adapted from Amy Bloom’s bestselling memoir. The film traces a marriage tested by Alzheimer’s and the couple’s decision to seek end-of-life care in Switzerland, with the screenplay co-written by Weitz and Bloom. Financing is in place through Anton, which is also handling international sales; U.S. rights are being co-represented with CAA Media Finance. Producers include Eddie Vaisman and Julia Lebedev for Sight Unseen, Andrew Miano and Weitz for Depth of Field, Clooney and Grant Heslov for Smokehouse Pictures, and Sébastian Raybaud for Anton.

The project arrives amid renewed industry interest in intimate adult dramas anchored by marquee talent. In a statement, Weitz called Bloom’s book “a contemporary fable of love, wit and existential stakes,” signaling a tone that blends candor with emotional rigor. Bloom praised the pairing of Clooney and Bening and said she was grateful the story “gets to be told on the screen… in Paul’s gifted hands.” No start date or distributor announcement has been made for the domestic release.

Bloom’s source material, published in 2022, recounts her husband Brian Ameche’s diagnosis and the couple’s path through legal and medical frameworks to a Swiss clinic that permits assisted death for eligible applicants. The film version retains that framework while foregrounding the partners’ decision-making and the practical realities surrounding it, an approach that reflects Bloom’s memoir and clarifies that the narrative is grounded in documented personal history rather than speculative fiction.

Packaging also underscores the commercial ambitions behind the film. Anton is fully financing, with international rights consolidated and U.S. sales positioned for a studio or prestige-label bid, a structure common to star-driven dramas built for awards-season corridors. With Clooney coming off high-profile work and Bening set for upcoming releases, In Love aligns two Oscar-recognized actors with a filmmaker whose recent projects have balanced mainstream reach and character-centric storytelling.